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Adult ADHD
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ADHD Medication Meta-analysis
Bupropion for attention deficit hyperactivity disorder (ADHD) in adults (Review)
Atomoxetine in ADHD Patients who use Marijuana
Do individuals with ADHD become more disinhibited with alcohol?
The Prevalence and Correlates of Adult ADHD in the United States: Results From the National Comorbidity Survey Replication
Cross-national prevalence and correlates of adult attention-deficit hyperactivity disorder
Comorbidity in adults with attention-deficit hyperactivity disorder
Toward systems neuroscience of ADHD: a meta-analysis of 55 fMRI studies
Adult ADHD & MRI
ADHD and Executive Function
Persistent ADHD Risk Factors
Does adult ADHD start during childhood?
Evidence for late onset ADHD
ADHD remission patterns in young adults
Persistent and late onset ADHD
Predictors of ADHD persistence in adulthood
Socioeconomic status and ADHD risk
Which symptoms resolve first in ADHD?
ADHD: Working Memory and Alpha Waves
Fitness and Executive Function in ADHD
Dopamine Receptors and ADHD
Anxiety, ADHD, and Cognitive Functioning
Executive functioning in adult ADHD: a meta-analytic review
ADHD Symptoms and Emotional Intelligence
ADHD, Attention, and Task Switching
Dopamine and Motivation in ADHD
ADHD, working memory, and verbal learning
ADHD and Forgetting
Sluggish Cognitive Tempo, ADHD, and Mind-Wandering
Medication and Training for Working Memory in ADHD
Long-Term Memory Performance in Adult ADHD
ADHD Symptoms and the Reward System
ADHD in high IQ adults
Can IQ compensate for ADHD symptoms?
IQ and ADHD have separate genetics
How ADHD and Test Taking Speed Affect Intelligence Testing
How IQ Compensates for ADHD in Executive Function
ADHD and estimated life expectancy
Irritability in ADHD
ADHD prevalence among adults with substance use disorder
Driving Anger and Driving Behavior in Adults With ADHD
Adult ADHD and Employment Stats
ADHD among adult workers
Maladaptive Daydreaming and Mental Health
Emotion dysregulation in adults with attention deficit hyperactivity disorder: a meta-analysis
ADHD and Comorbidity Statistics
ADHD and Empathy in Adults
Effects of ADHD in Parents
How do people with ADHD handle emotions?
Daydreaming and Attention in ADHD
Self-Esteem, Self-Efficacy, and Resources in Adults With ADHD
ADHD and Adjusting to College Life
ADHD, Executive Function, and Employment
ADHD and Anxiety: Clinical Significance and Treatment Implications
Vitamins, Minerals, and ADHD
Ritalin and Driving Ability
Does Ritalin improve your driving?
ADHD and Driving in Young Adults
Is Ritalin or Adderall better for driving?
Driving with ADHD and Alcohol
Do non-stimulant medications work for adult ADHD?
Ritalin: The effects of gender and alcohol
Ritalin reduces anxiety in cognitive test
Ritalin, reaction time, and response inhibition in healthy adults
Guanfacine vs Adderall for Adult ADHD
Venlafaxine for Adult ADHD
Ritalin may reduce anxiety in anxious adults without ADHD
Group CBT for Adult ADHD
Does CBT work well with medication for Adult ADHD?
CBT vs. Relaxation for Adult ADHD
ADHD and Skills Training Therapy
Mindfulness vs psychoeducation in adult ADHD: a randomized controlled trial
ADHD Psychotherapy and Skills Training
Structured Group Psychotherapy for ADHD
Efficacy of Meta-Cognitive Therapy (MCT) for Adult ADHD
Mindfulness CBT for ADHD
ADHD Medication and Blood Pressure
Working Memory and College Performance
Ritalin, Adderall, and Risks in Pregnancy
Atomoxetine in Adults with ADHD: Two Randomized, Placebo-Controlled Studies
Once-Daily Atomoxetine for Adult Attention-Deficit/Hyperactivity Disorder
Emotional dysregulation in adult ADHD and response to atomoxetine
Can you drink alcohol with Strattera (atomoxetine)?
Strattera and Social Anxiety in Adults
Effects of stimulants and atomoxetine on emotional lability in adults: A systematic review and meta-analysis
Atomoxetine treatment of adults with ADHD and comorbid alcohol use disorders
ADHD Meds & Heart Risk in Adults
Does Ritalin increase the risk of mania in those with Bipolar Disorder?
How often do teenagers use stimulants with other substances?
Irritability with Stimulants
Stimulant Medication and Substance Use Outcomes: A Meta-analysis

Visual Abstracts

A Placebo-Controlled Trial of Atomoxetine in Marijuana- Dependent Individuals with Attention Deficit Hyperactivity Disorder

Aimee L. McRae-Clark, PharmD, Rickey E. Carter, PhD, Therese K. Killeen, PhD, Matthew J. Carpenter, PhD, Kathleen G. White, BS, and Kathleen T. Brady, MD, PhD
Summarized by Charles Li, MD
July 25, 2022

🤔
Can atomoxetine be used to treat ADHD in marijuana users?
👍
A small clinical trial found that atomoxetine can reduce ADHD symptoms in marijuana users.
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However, it was unable to reduce the amount of marijuana used by the participants.
Visual Abstract
Click to expand

Methods and Objectives

Researchers wanted to see whether an ADHD medication, atomoxetine, could be used to treat ADHD and reduce marijuana use.

They recruited 38 adults who had ADHD and were dependent on marijuana.

They gave them either atomoxetine or a placebo control for 12 weeks and measured their ADHD symptoms and marijuana use.

Study Quote
McRae-Clark et al, 2010. Am J Addict.

This study evaluated the effects of atomoxetine on the symptoms of attention deficit hyperactivity disorder (ADHD) and marijuana use in marijuana-dependent adults. In conjunction with motivational interviewing, participants received either atomoxetine (n = 19) or matching placebo (n = 19...

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Results and Conclusions

They found that atomoxetine could reduce ADHD symptoms in marijuana users. Based on the clinician's assessment, those who were given the ADHD drug had significantly better symptoms after the trial than those given a placebo control.

A small clinical trial found that atomoxetine can treat ADHD symptoms in marijuana users.

However, there were no significant reductions in marijuana usage. Treating ADHD did not affect how much marijuana participants used.

While this trial was too small to evaluate side effects properly, they found that gastrointestinal and sexual side effects were the most common among participants given atomoxetine.

This trial was too small of a trial to draw firm conclusions on the effectiveness of atomoxetine in ADHD in marijuana users.

Among the small group studied, there weren't any unexpected side effects, which was encouraging. However, we'll need more studies in this area before we know for sure that atomoxetine is safe and effective when used with marijuana.

Study Quote
McRae-Clark et al, 2010. Am J Addict.

Participants randomized to atomoxetine had greater improvement in ADHD on the Clinical Global Impression-Improvement scale than participants treated with placebo. No treatment group differences in self-rated ADHD symptoms, overall Wender-Reimherr Adult Attention Deficit Disorder Scale sc...

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A small clinical trial found that atomoxetine can reduce ADHD symptoms among marijuana users. However, the study did not find differences in marijuana usage between the treatment and control groups.