This study examined the cardiovascular effects of Adderall (ADL) in youths aged 4 to 17 with ADHD. Patients were treated with either methylphenidate (MPH) twice daily or ADL once daily and evaluated under five conditions: baseline, placebo, and doses of 5 mg, 10 mg, or 15 mg. Resting pulse, diastolic blood pressure, and systolic blood pressure were measured after one week of treatment.

The results showed that both ADL and MPH had modest short-term cardiovascular effects, with no clinically significant changes observed in the patients' blood pressure or pulse during the trial.

This study compared the risk of cardiac events in youth using methylphenidate and amphetamine salts. It analyzed data from over 2 million children and adolescents enrolled in Florida Medicaid, focusing on those newly prescribed these medications for ADHD. Cardiac events were defined as emergency department (ED) visits for heart-related issues, and the study adjusted for various factors like age, gender, and medical history.

Results showed that the risk of cardiac ED visits was similar between current and former users of both methylphenidate and amphetamine salts.

This meta-analysis looked at different ADHD medications to see how effective and safe they are for children, adolescents, and adults. The researchers found that, in the short term, methylphenidate worked well for children and adolescents, while amphetamines were better for adults.

However, some medications had more side effects than others, especially amphetamines and modafinil. This study suggests which medications might be preferred based on age and side effects.

This study focused on evaluating how well Adderall works for children diagnosed with ADHD and what side effects they experience. 154 children participated, and they were given two different doses of Adderall. The results showed that Adderall had a high effectiveness rate, with 89% of children responding positively based on parent or teacher criteria. Parents also reported side effects like reduced appetite, stomachaches, and insomnia, especially at higher doses. These side effects were generally similar to those seen with other ADHD medications.

The study was conducted in a rural clinic, and children aged 5 to 18 years old were included. Adderall was compared with a placebo in a controlled setting, and each child served as their own control. The study used both parent and teacher observations to assess effectiveness.

Adderall, a medication frequently used to manage ADHD, is known to modestly affect heart rate and blood pressure. While studies indicate that these short-term changes are generally minor and not clinically significant, especially in youth, certain individuals may experience more pronounced effects. Regular cardiovascular monitoring is advised, particularly for those with preexisting heart conditions, to mitigate any potential risks associated with its use.

Comparative studies show that the risk of severe cardiac events does not significantly differ for methylphenidate and amphetamine salts, two common medications for ADHD, reinforcing the need for tailored treatment based on age and potential side effects. Additionally, peripheral vasculopathy is an associated risk, requiring vigilant observation and possible dose adjustments to prevent severe complications.