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The Impact of Childhood Attention-Deficit/Hyperactivity Disorder (ADHD) on Children's Health-Related Quality of Life: A Systematic Review and Meta-Analysis
Impact of Childhood ADHD on Health-Related Quality of Life
December 9, 2024
author
Wanni Arachchige Dona S, Badloe N, Sciberras E, Gold L, Coghill D, Le HND
journal
J Atten Disord
chart icon Visual
Original
Study Summary
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What They Studied
The study examined the link between children's health-related quality of life and childhood ADHD.
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What They Found
The study found a substantial reduction in health-related quality of life for children with ADHD, based on both parent and child reports.
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What This Means
These findings suggest that ADHD significantly lowers children's quality of life, highlighting how parents often report lower quality of life than children do themselves, adding to previous medication-focused studies like those on Methylphenidate and Adderall.
Study Overview
Background & Objectives
Ritalin, a central nervous stimulant, primarily treats ADHD in various age groups. It works by increasing norepinephrine and dopamine, essential chemicals in the brain. This has a profound impact, helping to manage symptoms.

The study delves into the link between children's health-related quality of life and ADHD, seeking insights into how ADHD affects day-to-day well-being among affected children.
Abstract: background
To investigate the association between children's health-related quality of life (HRQoL) and childhood attention-deficit/hyperactivity ...more
Study Summary
Methods
Scientists examined several databases for scholarly articles available from 2010 to 2022. Two independent reviewers were tasked with selecting and evaluating the quality of relevant studies.

They performed a meta-analysis, a statistical method to combine findings from studies that utilized the Pediatric Quality of Life Inventory (PedsQL), ensuring comprehensive insights from a vast amount of data.
Abstract: methods
Databases were systematically searched for peer-reviewed literature published between 2010 and 2022. Two reviewers independently screen...more
Study Results
Results
The researchers analyzed 23 studies, most of which were found to be of 'good' quality. The meta-analysis revealed that there is a notably significant difference in HRQoL between children with ADHD and those without.

Interestingly, parents consistently rated the quality of life lower for their children with ADHD than the children did themselves. However, this contrast wasn't observed between those with and without ADHD.
Abstract: results
Twenty-three studies were included, with most rated as "good" quality. Meta-analysis found "very large" effect in both parent- (Hedges'...more
Study Summary
Conclusions
The findings indicate that ADHD significantly diminishes children's HRQoL. The discrepancy in reporting between parents and children suggests differing perspectives on how ADHD affects daily life.

Parents recognized greater challenges or impacts on their children’s quality of life, pointing to a potential gap in perception or communication that might influence care strategies.
Abstract: conclusions
ADHD was associated with substantially poorer children's HRQoL. Among children with ADHD, parents rated their children's HRQoL lower than the children themselves.
Visual Summary for The Impact of Childhood Attention-Deficit/Hyperactivity Disorder (ADHD) on Children's Health-Related Quality of Life: A Systematic Review and Meta-Analysis
Clinical Guidelines
Guidelines suggest that psychometric testing with standardized behavior rating scales assists in ADHD diagnosis, reflecting clinical evaluations.

Comprehensive assessments should include environmental factors, considering family and school influences.

Behavioral therapy should complement medication for ADHD treatment.
Literature Review
Lee YC et al, undefined
Core Insight:Both papers indicate that children with ADHD have lower quality of life, as reported by both parents and children themselves, but the comparison paper highlights differences in reporting between ADHD children and those with typical development.
What It Adds:
Parent-Child Discrepancy Emphasized: The comparison paper shows parent-child gaps are larger in ADHD kids, especially in psychosocial aspects.
Psychosocial Impact Specifics: Both papers agree on lower reports from parents, but the comparison adds details on psychosocial reporting.
Literature Review
Lee YC et al, undefined
Core Insight:Both papers indicate that children with ADHD have lower quality of life, as reported by both parents and children themselves, but the comparison paper highlights differences in reporting between ADHD children and those with typical development.
What It Adds:
Parent-Child Discrepancy Emphasized: The comparison paper shows parent-child gaps are larger in ADHD kids, especially in psychosocial aspects.
Psychosocial Impact Specifics: Both papers agree on lower reports from parents, but the comparison adds details on psychosocial reporting.
Literature Review
Coghill et al.
Core Insight:Both papers show that ADHD is linked to worse quality of life compared to children without ADHD.
What It Adds:
Comparison Includes T1DM: This paper also compares ADHD to type 1 diabetes.
Correlated Ratings: Parent and child ratings of quality of life are similar but vary in strength.
Shared Themes:Both papers confirm that ADHD significantly impacts quality of life.
Literature Review
Coghill et al, 2017
Core Insight:Both papers find ADHD decreases health-related quality of life.
What It Adds:
Medication Impact: This paper shows meds help, especially for symptoms.